ABSTRACT
A 16-year-old girl had decrease in vision following dapsone overdose. This case demonstrated optical coherence tomography (OCT) evaluation of macular infarction following dapsone poisoning. OCT showed characteristic serial changes as Stage 1: Cystic macular edema, Stage 2: Resolving cystic change and Stage 3: Foveal atrophy. Hence, OCT could show the progression of foveal atrophy from cystic macular edema following dapsone poisoning.
Subject(s)
Adolescent , Dapsone/poisoning , Female , Follow-Up Studies , Humans , Infarction/chemically induced , Leprostatic Agents/poisoning , Macula Lutea/blood supply , Drug Overdose , Severity of Illness Index , Suicide, Attempted , Tomography, Optical Coherence/methods , Visual AcuityABSTRACT
Apresenta-se um caso de maculopatia isquêmica, secundária a injeção intravítrea de amicacina em paciente de 38 anos que apresentou endoftalmite após facoemulsificação com implante de lente intra-ocular. O tratamento foi realizado por meio de injeção intravítrea de amicacina, vancomicina e dexametasona. Após a melhora do quadro clínico, observou-se obstrução arteriolar na região macular. Embora a amicacina seja efetiva, por via intravítrea, para o tratamento de endoftalmite, pode causar infarto macular e baixa de acuidade visual significativa.
Subject(s)
Humans , Male , Adult , Amikacin/adverse effects , Anti-Bacterial Agents/adverse effects , Endophthalmitis/drug therapy , Infarction/chemically induced , Macula Lutea/blood supply , Vancomycin/adverse effects , Cataract Extraction/adverse effects , Endophthalmitis/etiology , Injections, Intralesional , Infarction/diagnosis , Visual AcuityABSTRACT
A 49-year-old woman presented with stupor and paraplegia following an induced hypotension. The temporal relationship to the induced hypotension and the absence of a clear embolic source on diagnostic tests support a causal association between the hypotensive episode and the ischemic infarct. However, despite the association, a cause-and-effect relationship could not be automatically inferred.